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J Bacteriol. 1970 July; 103(1): 32-36
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Genetic Mapping and Dominance of the Amber Suppressor, Su1 (supD), in Escherichia coli K-12¹

^a Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520

ABSTRACT

In this report Su1 (supD), which is known to suppress "amber" mutations by means of a specific transfer ribonucleic acid, has been mapped relative to his and uvrC and has been found to be located at about 37.5 min on the Taylor and Trotter genetic map of the Escherichia coli K-12 chromosome. In addition, Su1⁺ has been shown to be dominant over Su1^–, which supports the idea that Su1 is the structural gene for the suppressing transfer ribonucleic acid.

¹ This report is part of a thesis presented by E. P. H. to Yale University in partial fulfillment of the requirements for a Ph.D. degree.