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Genetic Analysis of a Large-Cell, Radiation-Resistant Strain of Escherichia coli¹

^a Argonne National Laboratory, Division of Biological and Medical Research, Argonne, Illinois 60439

ABSTRACT

A genetic analysis of Escherichia coli P6, a large-cell, radiation-resistant strain of E. coli, established that it originated as the result of a mutational event. The gene responsible for the complex P6 phenotype was located at 61 ± 0.5 min on the E. coli linkage map. The close resemblance of conjugal and transductional recombinants to one or the other parent without indication of an intermediate class suggests that only a single gene may be involved.

² Present address: International Minerals and Chemical Corp., Growth Sciences Center, Libertyville, Ill. 60048.

³ Present address: Department of Radiology and Radiation Biology, Colorado State University, Fort Collins, Col. 80521.

¹ Part of a thesis submitted by the senior author in partial fulfillment of the requirements for the Ph.D. degree, Illinois Institute of Technology, Chicago. A summary of this work was presented at the 68th Annual Meeting of the American Society for Microbiology, Detroit, Mich., 5-10 May 1968.

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