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J Bacteriol. 1970 December; 104(3): 1106-1109
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Inhibition of Colicin E2 Activity by Bacterial Lipopolysaccharide

Ying-Ying Chang and Lowell P. Hager

1 Department of Biochemistry, University of Illinois, Urbana, Illinois 61801

ABSTRACT

Lipopolysaccharide isolated from colicin E2-sensitive Escherichia coli and from "receptor-minus" mutants inhibits the activity of colicin E2. Lipid A and the polysaccharide fraction obtained by mild acid hydrolysis of lipopolysaccharide are inactive either alone or when tested in combination. Periodate oxidation of lipopolysaccharide destroys over 85% of its inhibition activity.

J Bacteriol. 1970 December; 104(3): 1106-1109
Copyright © 1970 American Society for Microbiology. All Rights Reserved.





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