JB
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by O'Donovan, G. A.
Right arrow Articles by Thomassen, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by O'Donovan, G. A.
Right arrow Articles by Thomassen, E.

 Previous Article  |  Next Article 

J Bacteriol. 1971 February; 105(2): 666-672
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Deoxycytidine Triphosphate Deaminase: Characterization of an Escherichia coli Mutant Deficient in the Enzyme

G. A. O'Donovan, G. Edlin1, J. A. Fuchs, J. Neuhard2 and E. Thomassen2

Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843
Enzyme Division, University Institute of Biological Chemistry B, Copenhagen K, Denmark

ABSTRACT

A mutant of Escherichia coli, previously shown to contain abnormal nucleoside triphosphate pools, was found to be defective in its ability to synthesize thymidine nucleotides. The defect is not in the enzyme thymidylate synthetase but in deoxycytidine triphosphate deaminase, an enzyme that supplies deoxyuridine monophosphate, the substrate for thymidylate synthetase.

FOOTNOTES

1 Present address: Department of Genetics, University of California, Davis, Calif. 95616.

2 Present address: Department of Bacteriology, University of California, Davis, Calif. 95616.

J Bacteriol. 1971 February; 105(2): 666-672
Copyright © 1971 American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Appl. Environ. Microbiol. Infect. Immun. Eukaryot. Cell
Mol. Cell. Biol. J. Virol. Microbiol. Mol. Biol. Rev.
ALL ASM JOURNALS

Copyright © 1971 by the American Society for Microbiology. All rights reserved.