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Induction of Mutants of Staphylococcus aureus 100 with Increased Ability to Produce Enterotoxin A

^a U.S. Army Biological Defense Research Laboratories, Fort Detrick, Frederick, Maryland 21701

ABSTRACT

As a result of serial exposures to a mutagenic agent, N-methyl-N'-nitro-N-nitrosoguanidine, the yield of enterotoxin A produced by the last mutant in the series was increased nearly 20-fold over the amount produced by the parent Staphylococcus aureus 100.

¹ Present address: Division of Research Grants, National Institutes of Health, Bethesda, Md. 20014.