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J Bacteriol. 1971 July; 107(1): 377-381
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Petite Mutation in Yeast

^a Department of Biochemistry and Department of Genetics (Division of Biological Sciences), Albert Einstein College of Medicine, Bronx, New York, 10461

ABSTRACT

A series of petite mutants of Saccharomyces cerevisiae, generated after treatment for various times with ethidium bromide, was isolated, and the mitochondrial deoxyribonucleic acid size for each member was estimated. It was found that, as the treatment time with ethidium bromide was increased, the mitochondrial deoxyribonucleic acid isolated from the petite series was increasingly reduced in size.

¹ Present address: Department of Microbiology, Papuan Medical College, Boroko, Territory of Papua and New Guinea.

² Present address: Division of Biology, California Institute of Technology, Pasadena, Calif. 91109.