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J Bacteriol. 1971 August; 107(2): 576-577
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Folate Replacement by Tetrahydrohomopteroate in Triazine-Resistant Bacteria¹

^a Christ Hospital Institute of Medical Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45219 and Department of Biochemistry and Pharmacology, Tufts University School of Medicine, Boston, Massachusetts 02111

ABSTRACT

Tetrahydrohomopteroate, which inhibits the growth of Streptococcus faecium (Streptococcus faecalis ATCC 8043), replaces folate as a growth factor in chlorguanide triazine-resistant strains of this organism.

¹ Contribution no. 545 from the Army Research Program on Malaria.