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J Bacteriol. 1971 November; 108(2): 844-848
Copyright © 1971 American Society for Microbiology. All Rights Reserved.

Effects of Various Drugs on Hemolytic Activity of Streptococcus zymogenes

Jean M. Werth and Robert W. Jackson

1 Department of Biology, Syracuse University, Syracuse, New York 13210

ABSTRACT

Drugs known to interrupt the chain of protein synthesis (streptomycin, chloramphenicol, ethidium bromide) appeared to affect production of the group D lysin by Streptococcus zymogenes by inhibiting growth. Drugs which block cell wall synthesis (vancomycin, bacitracin, D-cycloserine, and phosphonomycin) inhibited lytic activity by a mechanism independent of growth. Bacitracin appeared not to have a major effect on lysin production but elicited the production of an inhibitor of lytic activity.

J Bacteriol. 1971 November; 108(2): 844-848
Copyright © 1971 American Society for Microbiology. All Rights Reserved.





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Appl. Environ. Microbiol. Infect. Immun. Eukaryot. Cell
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