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J Bacteriol. 1972 January; 109(1): 416-422
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Naturally Occurring R Factor, Derepressed for Pilus Synthesis, Belonging to the Same Compatibility Group as the Sex Factor F of Escherichia coli K-12

^a Bacteriology Department, Royal Postgraduate Medical School, London W 12, England

ABSTRACT

A naturally occurring R factor with constitutive pilus synthesis is described which resembles the sex factor F in compatibility and in restricting coliphage T7. Unlike F, it is not cured during growth with acridine orange. Results suggest that the R factor produces repressor of pilus synthesis, to which the operator is insensitive (i⁺o^c). In this respect it differs from both the F factor (i^–o⁺) and wild-type F-like R factors (i⁺o⁺).

¹ Present address: Department of Genetics, The University of Leeds, Leeds, England.