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J Bacteriol. 1972 January; 109(1): 447-449
Copyright © 1972 American Society for Microbiology. All Rights Reserved.
1 Department of Microbiology, Yale University School of Medicine, New Haven, Connecticut 06510
ABSTRACT
Wild-type sex factors of Escherichia coli K-12 can be cured from host cells by growth at temperatures above 42 C. This phenomenon is obscured by reinfection of cured cells if the culture is allowed to reach cell densities above 105/ml. The rate of episome loss is dependent on the genetic (chromosomal) background of the host.
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