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J Bacteriol. 1972 February; 109(2): 560-564
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Identification of Competence-Repressing Factors During Log-Phase Growth of Haemophilus influenzae

Donald H. Miller1 and P. C. Huang2

a Department of Biochemistry, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland 21205

ABSTRACT

Metabolic factors that suppress development of competence in Haemophilus influenzae during growth in the synthetic medium MIc have been identified. These include inosine, nicotinamide adenine dinucleotide, glycerol, and uracil. It is also possible to initiate competence in the presence of these substances if the oxygen tension in the culture is temporarily reduced.


FOOTNOTES

1 Present address: Department of Molecular Biology, Max Planck Institute for Experimental Medicine, Goettingen, Germany.

2 To whom inquiries should be directed.


J Bacteriol. 1972 February; 109(2): 560-564
Copyright © 1972 American Society for Microbiology. All Rights Reserved.







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