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J Bacteriol. 1972 May; 110(2): 761-763
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Isoleucine Accumulation by Regulatory Mutants of Serratia marcescens: Lack of Both Feedback Inhibition and Repression

Masahiko Kisumi, Saburo Komatsubara, Masaki Sugiura and Ichiro Chibata

Department of Applied Biochemistry, Chemical Research Laboratory, Tanabe Seiyaku Co., Ltd., Kashima-cho, Higashiyodogawa-ku, Osaka, Japan

ABSTRACT

Double mutants of Serratia marcescens resistant to isoleucine hydroxamate and {alpha}-aminobutyric acid accumulated large amounts of isoleucine in a salts-sugar medium and lacked both feedback inhibition and repression of the isoleucine biosynthesis.


J Bacteriol. 1972 May; 110(2): 761-763
Copyright © 1972 American Society for Microbiology. All Rights Reserved.







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