This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Oltmanns, O. Articles by Bacher, A. Search for Related Content PubMed PubMed Citation Articles by Oltmanns, O. Articles by Bacher, A.

Biosynthesis of Riboflavine in Saccharomyces cerevisiae: the Role of Genes rib₁ and rib₇

Institut für Mikrobiologie und Molekularbiologie, Universität Hohenheim, 7 Stuttgart 70, Germany

ABSTRACT

Haploid strains of Saccharomyces cerevisiae with mutations in two different rib genes were constructed. These strains were studied by tetrad analysis and by quantitative determination of accumulation products. The genes rib₁, rib₇, and rib₂ are not linked to each other. rib₁-rib₇ strains and rib₁-rib₂ strains exhibit the phenotypic properties of rib₁ strains. rib₇-rib₂ strains show the phenotypic properties of rib₇ strains. The results support the conclusion that the genes rib₁ and rib₇ code for the first and second enzyme of the riboflavine pathway, respectively.

This article has been cited by other articles:

• Chen, S.-C., Chang, Y.-C., Lin, C.-H., Lin, C.-H., Liaw, S.-H. (2006). Crystal Structure of a Bifunctional Deaminase and Reductase from Bacillus subtilis Involved in Riboflavin Biosynthesis. J. Biol. Chem. 281: 7605-7613 [Abstract] [Full Text]  
• Fischer, M., Romisch, W., Saller, S., Illarionov, B., Richter, G., Rohdich, F., Eisenreich, W., Bacher, A. (2004). Evolution of Vitamin B2 Biosynthesis: STRUCTURAL AND FUNCTIONAL SIMILARITY BETWEEN PYRIMIDINE DEAMINASES OF EUBACTERIAL AND PLANT ORIGIN. J. Biol. Chem. 279: 36299-36308 [Abstract] [Full Text]  
• García-Ramírez, J. J., Santos, M. A., Revuelta, J. L. (1995). The Saccharomyces cerevisiae RIB4 Gene Codes for 6,7-Dimethyl- 8-ribityllumazine Synthase Involved in Riboflavin Biosynthesis. J. Biol. Chem. 270: 23801-23807 [Abstract] [Full Text]  
• Santos, M. A., García-Ramírez, J. J., Revuelta, J. L. (1995). Riboflavin Biosynthesis in Saccharomyces cerevisiae. J. Biol. Chem. 270: 437-444 [Abstract] [Full Text]