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Mapping of the fabA Locus for Unsaturated Fatty Acid Biosynthesis in Escherichia coli

¹ Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06510
Department of Biological Chemistry, Washington University School of Medicine, St. Louis, Missouri 63110
Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92664

ABSTRACT

fabA mutants of Escherichia coli require an appropriate unsaturated fatty acid for growth. The fabA locus has now been mapped at minute 21.5 of the linkage map of E. coli. The locus is cotransduced with pyrD and aroA but not with pyrC, purB, or pdxC. The clockwise order of markers in the region is pdxC, aroA, cmlB, pyrD, fabA, pyrC.

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• Wang, H., Cronan, J. E. (2004). Functional Replacement of the FabA and FabB Proteins of Escherichia coli Fatty Acid Synthesis by Enterococcus faecalis FabZ and FabF Homologues. J. Biol. Chem. 279: 34489-34495 [Abstract] [Full Text]