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Host Cell Deoxyribonucleic Acid Polymerase I and the Support of T4 Bacteriophage Growth

Department of Biological Sciences, Douglass College, Rutgers-The State University, New Brunswick, New Jersey 08903

ABSTRACT

Ultraviolet irradiation of Escherichia coli polA^– cells reduces their capacity to support the growth of T4 phage. There is no additional loss of capacity observed in pol tsA^–recA^– double mutants at the nonpermissive temperature. The reversion frequency of a T4 rII mutant after ultraviolet irradiation is not changed by the absence of host deoxyribonucleic acid polymerase I.