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J Bacteriol. 1972 December; 112(3): 1444-1445
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Comparative Effect of Oxygen and Nitrate on Protoporphyrin and Heme Synthesis from -Amino Levulinic Acid in Bacterial Cultures

Department of Microbiology, Dartmouth Medical School, Hanover, New Hampshire 03755

ABSTRACT

Pseudomonas aeruginosa and P. denitrificans accumulate more protoheme and considerably more protoporphyrin during anaerobic growth under denitrifying conditions than during aerobic growth. In Escherichia coli, the small accumulation of protoporphyrin and protoheme which occurs during anaerobic growth is slightly stimulated by nitrate and markedly stimulated by oxygen.

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