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J Bacteriol. 1973 April; 114(1): 457-459
Copyright © 1973 American Society for Microbiology. All Rights Reserved.

New Pathway for Nonphosphorylated Degradation of Gluconate by Aspergillus niger

Laboratory of Microbial Chemistry, National Research Center, Dokki, Cairo, Egypt

ABSTRACT

A new nonphosphorylative pathway for gluconate degradation was found in extracts of a strain of Aspergillus niger. The findings indicate that gluconate is dehydrated into 2-keto-3-deoxy-gluconate (KDG), which then is cleaved into glyceraldehyde and pyruvate. 6-Phosphogluconate was not degraded under the same conditions. In addition, KDG was formed from glyceraldehyde and pyruvate. Very weak activity was obtained when glyceraldehyde 3-phosphate replaced glyceraldehyde in this reaction.

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