This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Setlow, P. Search for Related Content PubMed PubMed Citation Articles by Setlow, P.

 Previous Article  |  Next Article 

J Bacteriol. 1973 June; 114(3): 1099-1107
Copyright © 1973 American Society for Microbiology. All Rights Reserved.

Deoxyribonucleic Acid Synthesis and Deoxynucleotide Metabolism During Bacterial Spore Germination

^a The Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, and the Department of Biochemistry, University of Connecticut Health Center, Farmington, Connecticut 06032

ABSTRACT

Deoxyribonucleic acid (DNA) synthesis during germination of Bacillus megaterium spores takes place in two stages. In stage I (0-55 min) DNA synthesis is slow and there is no detectable net synthesis, whereas in stage II (from 55 min on) the rate of synthesis is much faster and net DNA synthesis occurs. Deoxyribonucleotide pool sizes match the rates of DNA synthesis in stages I and II. The level of deoxyribonucleotide triphosphates is not correlated with the level of deoxyribonucleotide kinases, but rather with that of ribonucleotide reductase activity.

¹ Present address: Department of Biochemistry, University of Connecticut Health Center, Farmington, Conn. 06032.

This article has been cited by other articles:

• Castellanos-Juarez, F. X., Alvarez-Alvarez, C., Yasbin, R. E., Setlow, B., Setlow, P., Pedraza-Reyes, M. (2006). YtkD and MutT Protect Vegetative Cells but Not Spores of Bacillus subtilis from Oxidative Stress. J. Bacteriol. 188: 2285-2289 [Abstract] [Full Text]