J Bacteriol. 1974 January; 117(1): 283-289
Copyright © 1974 American Society for Microbiology. All Rights Reserved.
Characterization of Three Plasmid Deoxyribonucleic Acid Molecules in a Strain of Streptococcus faecalis: Identification of a Plasmid Determining Erythromycin Resistance
D. B. Clewell,
Y. Yagi,
G. M. Dunny and
S. K. Schultz
1 Dental Research Institute, Departments of Oral Biology and Microbiology, Schools of Dentistry and Medicine, The University of Michigan, Ann Arbor, Michigan 48104
ABSTRACT
Three plasmids designated
, ß, and
, distinguishable by their molecular weights (6, 17, and 34 million, respectively) were isolated from Streptococcus faecalis strain DS-5 (ATCC 14508). Derivatives of this strain "cured" for erythromycin resistance lacked the ß-plasmid. In the parent strain the ß-plasmid was estimated to be present to the extent of one to two copies per chromosomal genome equivalent whereas the
- and
-plasmids were about nine and five copies, respectively.
J Bacteriol. 1974 January; 117(1): 283-289
Copyright © 1974 American Society for Microbiology. All Rights Reserved.
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Copyright © 1974 by the American Society for Microbiology. All rights reserved.