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R62, a Naturally Occurring Hybrid R Plasmid

¹ University of Washington School of Medicine, Department of Microbiology, Seattle, Washington 98195, and Royal Postgraduate Medical School, London, United Kingdom

ABSTRACT

R62, a naturally occurring R factor, was shown to be a single deoxyribonucleic acid molecule composed of polynucleotide sequences typical of I group plasmids and also sequences typical of the N group. It determined I pili and belonged to the I compatibility group. Although compatible with plasmids of group N, R62 showed complex genetic reactions with N plasmids which are described and interpreted. It is concluded that R62 was the product of illegitimate recombination between an I group and an N group plasmid.