This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Wang, C. S. Articles by Alaupovic, P. Search for Related Content PubMed PubMed Citation Articles by Wang, C. S. Articles by Alaupovic, P.

Isolation and Composition of Oligosaccharide Cores from Endotoxins of Two Serratia marcescens Strains

¹ Lipoprotein Laboratory, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104; and Department of Biochemistry and Molecular Biology, University of Oklahoma School of Medicine, Oklahoma City, Oklahoma 73104

ABSTRACT

The oligosaccharide cores isolated from the acetic acid hydrolysates of endotoxins from Serratia marcescens 08 and Serratia marcescens Bizio were analyzed for their sugar composition. The intact oligosaccharide core from S. marcescens 08 consisted of 2-keto-3-deoxyoctonate, D-glycero-D-mannoheptose, L-glycero-D-mannoheptose, D-glucose, D-galactose, and D-glucosamine in a molar ratio of 2:1:5:3:1:3 and that from S. marcescens Bizio consisted of the same sugar components in a molar ratio of 2:1:5:5:1:2. This result indicates that endotoxins from S. marcescens genus may contain more than one structural type of oligosaccharide core. Both oligosaccharide cores also differ in their chemical compositions from cores of other Enterobacteriaceae.