This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Matthew, M Articles by Hedges, R W Search for Related Content PubMed PubMed Citation Articles by Matthew, M Articles by Hedges, R W

 Previous Article  |  Next Article 

J Bacteriol. 1976 February; 125(2): 713-718

Analytical isoelectric focusing of R factor-determined beta-lactamases: correlation with plasmid compatibility.

ABSTRACT

R factor-determined beta-lactamases have been investigated by analytical isoelectric focusing. The enzymes such as those specified by the R6K and RP4 plasmids (TEM-type enzymes) are notably homogenous in biochemical tests (Hedges et al., 1974), but two subclasses can be distinguished by isoelectric focusing. Three subclasses can be distinguished among the oxacillin-hydrolyzing enzymes, in good agreement with the classification based upon biochemical characteristics (Dale and Smith, 1974). The TEM-type beta-lactamases are promiscuously distributed among plasmids of a wide variety of compatibility groups, whereas the various oxacillin-hydrolyzing enzymes show some degree of correlation with compatibility.

This article has been cited by other articles:

• Jacoby, G. A. (2006). {beta}-Lactamase Nomenclature.. Antimicrob. Agents Chemother. 50: 1123-1129 [Full Text]  
• Eckert, C., Gautier, V., Saladin-Allard, M., Hidri, N., Verdet, C., Ould-Hocine, Z., Barnaud, G., Delisle, F., Rossier, A., Lambert, T., Philippon, A., Arlet, G. (2004). Dissemination of CTX-M-Type {beta}-Lactamases among Clinical Isolates of Enterobacteriaceae in Paris, France. Antimicrob. Agents Chemother. 48: 1249-1255 [Abstract] [Full Text]  
• Heritage, J., M'Zali, F. H., Gascoyne-Binzi, D., Hawkey, P. M. (1999). Evolution and spread of SHV extended-spectrum {beta}-lactamases in Gram-negative bacteria. J Antimicrob Chemother 44: 309-318 [Abstract] [Full Text]  
• Caniça, M. M., Caroff, N., Barthélémy, M., Labia, R., Krishnamoorthy, R., Paul, G., Dupret, J.-M. (1998). Phenotypic Study of Resistance of beta -Lactamase-Inhibitor-Resistant TEM Enzymes Which Differ by Naturally Occurring Variations and by Site-Directed Substitution at Asp276. Antimicrob. Agents Chemother. 42: 1323-1328 [Abstract] [Full Text]