This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Bohin, J P Articles by Schaeffer, P Search for Related Content PubMed PubMed Citation Articles by Bohin, J P Articles by Schaeffer, P

 Previous Article  |  Next Article 

J Bacteriol. 1976 August; 127(2): 934-940

Ethanol sensitivity of sporulation in Bacillus subtilis: a new tool for the analysis of the sporulation process.

ABSTRACT

The growth rate of Bacillus subtilis is lowered but the final cell yield is unchanged when certain concentrations of ethanol are present in the culture medium. At the concentration allowing growth at half-maximal rate, practically no spores are formed. Blockage of spore formation generally occurs at stage 0-I. Sensitivity to ethanol of the capacity to form spores is limited, in a nonsynchronized culture, to a period of at most 45 min around t1. Postexponential events such as excretion of certain enzymes and modification of ribonucleic acid polymerase are altered or suppressed in the presence of ethanol, possibly as the results of a physical change upon the cell membrane. In effect, ethanol is turning wild-type cells into phenocopies of spoO mutants.

This article has been cited by other articles:

• Gottig, N., Pedrido, M. E., Mendez, M., Lombardia, E., Rovetto, A., Philippe, V., Orsaria, L., Grau, R. (2005). The Bacillus subtilis SinR and RapA Developmental Regulators Are Responsible for Inhibition of Spore Development by Alcohol. J. Bacteriol. 187: 2662-2672 [Abstract] [Full Text]  
• Vulic, M., Kolter, R. (2002). Alcohol-Induced Delay of Viability Loss in Stationary-Phase Cultures of Escherichia coli. J. Bacteriol. 184: 2898-2905 [Abstract] [Full Text]