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J Bacteriol. 1976 September; 127(3): 1136-1140

Synthesis of omega-alicyclic fatty acids from cyclic precursors in Bacillus subtilis.

R Dreher, K Poralla and W A König

ABSTRACT

A mutant of Bacillus subtilis synthesizes a variety of omega-alicyclic fatty acids when fed with the respective alicyclic carboxylic acids. These fatty acids are: omega-cyclopropane, omega-cyclobutane, omega-cyclopentane, omega-cyclohexane, and omega-cyclohexene fatty acids. These unusual fatty acids did not lead to an inhibition of growth at 37 degrees C and pH 7. The selective advantage of these fatty acids under extrene conditions was studied in comparison with the acidophilic, thermophilic bacterium B. acidocaldarius, which normally contains a high proportion of omega-cyclohexane fatty acids.

J Bacteriol. 1976 September; 127(3): 1136-1140






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