This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Sprague, G F Articles by Cronan, J E Search for Related Content PubMed PubMed Citation Articles by Sprague, G F Articles by Cronan, J E

 Previous Article  |  Next Article 

J Bacteriol. 1977 March; 129(3): 1335-1342

Isolation and characterization of Saccharomyces cerevisiae mutants defective in glycerol catabolism.

ABSTRACT

Mutants of the yeast Saccharomyces cerevisiae that are defective in the catabolism of glycerol were isolated, and two types of mutants were obtained. One type was deficient in glycerol kinase activity, whereas the other type was deficient in sn-glycerol 3-phosphate dehydrogenase activity. Genetic analysis indicated that each mutant strain owed its phenotype to a single nuclear mutation, and that the two mutations were complementary. The mutations were not linked to each other or to any of 10 loci tested. In addition, neither mutation was centromere linked. Possible mechanisms for the regulation of these enzymes were tested by growing the parental strain in the presence of various carbon sources.

This article has been cited by other articles:

• Hohmann, S. (2002). Osmotic Stress Signaling and Osmoadaptation in Yeasts. Microbiol. Mol. Biol. Rev. 66: 300-372 [Abstract] [Full Text]  
• Karpichev, I. V., Cornivelli, L., Small, G. M. (2002). Multiple Regulatory Roles of a Novel Saccharomyces cerevisiae Protein, Encoded by YOL002c, in Lipid and Phosphate Metabolism. J. Biol. Chem. 277: 19609-19617 [Abstract] [Full Text]  
• Gancedo, J. M. (1998). Yeast Carbon Catabolite Repression. Microbiol. Mol. Biol. Rev. 62: 334-361 [Abstract] [Full Text]  
• Pahlman, A.-K., Granath, K., Ansell, R., Hohmann, S., Adler, L. (2001). The Yeast Glycerol 3-Phosphatases Gpp1p and Gpp2p Are Required for Glycerol Biosynthesis and Differentially Involved in the Cellular Responses to Osmotic, Anaerobic, and Oxidative Stress. J. Biol. Chem. 276: 3555-3563 [Abstract] [Full Text]