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J Bacteriol. 1978 December; 136(3): 955-959

Inactivation of the chemoattractant folic acid by cellular slime molds and identification of the reaction product.

P Pan and B Wurster

ABSTRACT

Enzymes inactivating the chemoattractants folic acid and pterin were detected in extracellular, intracellular, and particulate fractions obtained from Dictyostelium discoideum strains NC4 and AX-2 and Polysphondylium violaceum. The products of the inactivation reaction were analyzed by thin-layer chromatography and UV spectroscopy. Results obtained indicate that folic acid and pterin were deaminated to 2-deamino folic acid and lumazine, respectively.

J Bacteriol. 1978 December; 136(3): 955-959






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