This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Beutin, L Articles by Achtman, M Search for Related Content PubMed PubMed Citation Articles by Beutin, L Articles by Achtman, M

 Previous Article  |  Next Article 

J Bacteriol. 1979 September; 139(3): 730-737

Two Escherichia coli chromosomal cistrons, sfrA and sfrB, which are needed for expression of F factor tra functions.

ABSTRACT

Twelve mutants of Escherichia coli K-12 have been isolated which carry chromosomal mutations that exhibit pleiotropic effects on the expression of F factor tra cistrons. F pilus synthesis, deoxyribonucleic acid transfer, and surface exclusion are all inhibited. Six of the mutants carry sfrA mutations, and six carry sfrB mutations. sfrA and sfrB are cistrons mapping near thr and metE, respectively. Several F-like plasmids are dependent on sfrA and on sfrB for expression of tra cistrons. Plasmids of incompatibility groups C and S are only dependent on sfrB,and other conjugative plasmids are dependent on neither. sfrB mutations also result in changes in certain cell envelope properties, including change sensitivity to certain bacteriophages which use lipopolysaccharide as a receptor, synthesis of nonfunctional flagella, and altered sensitivity to antibiotics.

This article has been cited by other articles:

• Spitzer, D., Mitchell, L. M., Atkinson, J. P., Hourcade, D. E. (2007). Properdin Can Initiate Complement Activation by Binding Specific Target Surfaces and Providing a Platform for De Novo Convertase Assembly. J. Immunol. 179: 2600-2608 [Abstract] [Full Text]  
• Bidlack, J. E., Silverman, P. M. (2004). An Active Type IV Secretion System Encoded by the F Plasmid Sensitizes Escherichia coli to Bile Salts. J. Bacteriol. 186: 5202-5209 [Abstract] [Full Text]  
• Carter, H. D., Svetlov, V., Artsimovitch, I. (2004). Highly Divergent RfaH Orthologs from Pathogenic Proteobacteria Can Substitute for Escherichia coli RfaH both In Vivo and In Vitro. J. Bacteriol. 186: 2829-2840 [Abstract] [Full Text]  
• Maidhof, H., Guerra, B., Abbas, S., Elsheikha, H. M., Whittam, T. S., Beutin, L. (2002). A Multiresistant Clone of Shiga Toxin-Producing Escherichia coli O118:[H16] Is Spread in Cattle and Humans over Different European Countries. Appl. Environ. Microbiol. 68: 5834-5842 [Abstract] [Full Text]  
• Bittner, M., Saldias, S., Estevez, C., Zaldivar, M., Marolda, C. L., Valvano, M. A., Contreras, I. (2002). O-antigen expression in Salmonella enterica serovar Typhi is regulated by nitrogen availability through RpoN-mediated transcriptional control of the rfaH gene. Microbiology 148: 3789-3799 [Abstract] [Full Text]  
• Strauch, E., Lurz, R., Beutin, L. (2001). Characterization of a Shiga Toxin-Encoding Temperate Bacteriophage of Shigella sonnei. Infect. Immun. 69: 7588-7595 [Abstract] [Full Text]  
• Marolda, C. L., Valvano, M. A. (1998). . J. Bacteriol. 180: 3070-3079 [Abstract] [Full Text]  
• Zechner, E. L., Pruger, H., Grohmann, E., Espinosa, M., Hogenauer, G. (1997). Specific cleavage of chromosomal and plasmid DNA strands in gram-positive and gram-negative bacteria can be detected with nucleotide resolution. Proc. Natl. Acad. Sci. USA 94: 7435-7440 [Abstract] [Full Text]