This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Singer, M Articles by Gross, C A Search for Related Content PubMed PubMed Citation Articles by Singer, M Articles by Gross, C A

research-article

The Escherichia coli ts8 mutation is an allele of fda, the gene encoding fructose-1,6-diphosphate aldolase.

Department of Bacteriology, University of Wisconsin-Madison 53706.

ABSTRACT

The ts8 mutant of Escherichia coli has previously been shown to preferentially inhibit stable RNA synthesis when shifted to the nonpermissive temperature. We demonstrate in this report that the ts8 mutation is an allele of fda, the gene that encodes the glycolytic enzyme fructose-1,6-diphosphate aldolase. We show that ts8 and a second fda mutation, h8, isolated and characterized by A. Böck and F. C. Neidhardt, are dominant mutations and that they encode a thermolabile aldolase activity.

This article has been cited by other articles:

• Schneider, D. A., Gourse, R. L. (2003). Changes in the Concentrations of Guanosine 5'-Diphosphate 3'-Diphosphate and the Initiating Nucleoside Triphosphate Account for Inhibition of rRNA Transcription in Fructose-1,6-Diphosphate Aldolase (fda) Mutants. J. Bacteriol. 185: 6192-6194 [Abstract] [Full Text]  
• Morita, T., El-Kazzaz, W., Tanaka, Y., Inada, T., Aiba, H. (2003). Accumulation of Glucose 6-Phosphate or Fructose 6-Phosphate Is Responsible for Destabilization of Glucose Transporter mRNA in Escherichia coli. J. Biol. Chem. 278: 15608-15614 [Abstract] [Full Text]