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J Bacteriol. 1992 October; 174(19): 6311-6313

research-article

DNA polymerase I modulates inducible stable DNA replication in Escherichia coli.

T Ruscitti and S Linn

Division of Biochemistry and Molecular Biology, University of California, Berkeley 94720.

ABSTRACT

Mutants of Escherichia coli lacking RNase HI activity and cells induced for the SOS response express modes of DNA replication independent of protein synthesis, called constitutive and induced stable DNA replication, respectively. We report here that mutants deleted for the polA gene express induced stable DNA replication at approximately 25-fold the rate of wild-type cells, whereas constitutive stable DNA replication is not enhanced.

J Bacteriol. 1992 October; 174(19): 6311-6313






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Appl. Environ. Microbiol. Infect. Immun. Eukaryot. Cell
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Copyright © 1992 by the American Society for Microbiology. All rights reserved.