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J Bacteriol. 1992 January; 174(2): 643-645

research-article

Fumarate or a fumarate metabolite restores switching ability to rotating flagella of bacterial envelopes.

Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot, Israel.

ABSTRACT

Flagella of cytoplasm-free envelopes of Escherichia coli or Salmonella typhimurium can rotate in either the counterclockwise or clockwise direction, but they never switch from one direction of rotation to another. Exogenous fumarate, in the intracellular presence of the chemotaxis protein CheY, restored switching ability to envelopes, with a concomitant increase in clockwise rotation. An increase in clockwise rotation was also observed after fumarate was added to partially lysed cells of E. coli, but the proportion of switching cells remained unchanged.

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