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J Bacteriol. 1993 June; 175(12): 3916-3917

research-article

Plasmid pT181-linked suppressors of the Staphylococcus aureus pcrA3 chromosomal mutation.

S Iordanescu

Public Health Research Institute, New York, New York 10016.

ABSTRACT

Plasmid pT181 replication is affected in hosts carrying the chromosomal pcrA3 mutation, resulting in significantly lower plasmid copy numbers. Mutations suppressing this effect have been isolated and characterized. The suppressor mutations were found to map in the plasmid repC gene and manifested pcrA allele specificity, suggesting the existence of a direct RepC-PcrA interaction.


J Bacteriol. 1993 June; 175(12): 3916-3917




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Appl. Environ. Microbiol. Infect. Immun. Eukaryot. Cell
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Copyright © 1993 by the American Society for Microbiology. All rights reserved.