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J Bacteriol. 1993 July; 175(13): 4235-4238

research-article

The INO1 promoter of Saccharomyces cerevisiae includes an upstream repressor sequence (URS1) common to a diverse set of yeast genes.

Department of Molecular and Cellular Biochemistry, Stritch School of Medicine, Loyola University, Chicago, Maywood, Illinois 60153.

ABSTRACT

The INO1 promoter of Saccharomyces cerevisiae includes a copy of an upstream repression sequence (URS1; 5'AGCCGCCGA 3') observed in the promoters of several unrelated yeast genes. Expression of INO1-lacZ and CYC1-lacI'Z, activated by the INO1 UASINO, is significantly decreased by the INO1 URS1.

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