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J Bacteriol. 1993 November; 175(22): 7471-7473

research-article

Resistance of lambda cI translation to antibiotics that inhibit translation initiation.

Institute of Cancer Research, Columbia University College of Physicians and Surgeons, New York, New York 10032.

ABSTRACT

The lambda cI lysogenic transcript is unusual in having no leader. Expression of a cI-lacZ protein fusion was relatively resistant to kasugamycin and pactamycin, which inhibit translation initiation on transcripts with leaders. Our data imply that there are distinct differences in translation initiation between the two classes of transcripts.

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