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research-article

Heterogeneity of small plasmids from halophilic archaea.

Belozersky Laboratory of Molecular Biology and Bioorganic Chemistry, Moscow State University, Russia.

ABSTRACT

Small multicopy plasmids in three strains of halophilic archaea, SB3, GRB, and GN101, were found to be present in a cell as a population of related but not identical sequences. Two types of heterogeneity were observed: macroheterogeneity, represented by two major plasmid sequence versions homologous to each other by 80%, and microheterogeneity, in which individual plasmids differ by one or a few nucleotide substitutions.

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