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Inhibition of Escherichia coli chemotaxis by omega-conotoxin, a calcium ion channel blocker.

Department of Biochemistry, University of Wisconsin-Madison 53706-1569.

ABSTRACT

Escherichia coli chemotaxis was inhibited by omega-conotoxin, a calcium ion channel blocker. With Tris-EDTA-permeabilized cells, nanomolar levels of omega-conotoxin inhibited chemotaxis without loss of motility. Cells treated with omega-conotoxin swam with a smooth bias, i.e., tumbling was inhibited.

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