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J Bacteriol. 1994 October; 176(20): 6404-6406

research-article

Additive effect of tolC and rfa mutations on the hydrophobic barrier of the outer membrane of Escherichia coli K-12.

Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock 79430.

ABSTRACT

Studies using tolC mutant derivatives of deep rough (rfa) mutants indicate that tolC and rfa mutations have an additive effect with respect to their sensitivity to hydrophobic agents, suggesting that they are not acting through a mutual mechanism to alter the permeability of the outer membrane.

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