This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Wriedt, K. Articles by Braun, V. Search for Related Content PubMed PubMed Citation Articles by Wriedt, K. Articles by Braun, V.

 Previous Article  |  Next Article 

J. Bacteriol., Jun 1995, 3320-3322, Vol 177, No. 11
Copyright © 1995, American Society for Microbiology

Transcriptional regulation from the cell surface: conformational changes in the transmembrane protein FecR lead to altered transcription of the ferric citrate transport genes in Escherichia coli

K Wriedt, A Angerer and V Braun
Universitat Tubingen, Germany.

Ferric citrate induces the ferric citrate transport system in Escherichia coli without being taken up into cells. The cytoplasmic transmembrane protein FecR, required for the response to ferric citrate, was found to be cleaved by a cellular protease. FecR protein produced by fecR mutants impaired or constitutive in fecA transcription was protease resistant, indicating that conformational changes affect proper functioning of FecR.

This article has been cited by other articles:

• Enz, S., Brand, H., Orellana, C., Mahren, S., Braun, V. (2003). Sites of Interaction between the FecA and FecR Signal Transduction Proteins of Ferric Citrate Transport in Escherichia coli K-12. J. Bacteriol. 185: 3745-3752 [Abstract] [Full Text]  
• Mahren, S., Enz, S., Braun, V. (2002). Functional Interaction of Region 4 of the Extracytoplasmic Function Sigma Factor FecI with the Cytoplasmic Portion of the FecR Transmembrane Protein of the Escherichia coli Ferric Citrate Transport System. J. Bacteriol. 184: 3704-3711 [Abstract] [Full Text]  
• Stiefel, A., Mahren, S., Ochs, M., Schindler, P. T., Enz, S., Braun, V. (2001). Control of the Ferric Citrate Transport System of Escherichia coli: Mutations in Region 2.1 of the FecI Extracytoplasmic-Function Sigma Factor Suppress Mutations in the FecR Transmembrane Regulatory Protein. J. Bacteriol. 183: 162-170 [Abstract] [Full Text]  
• Enz, S., Mahren, S., Stroeher, U. H., Braun, V. (2000). Surface Signaling in Ferric Citrate Transport Gene Induction: Interaction of the FecA, FecR, and FecI Regulatory Proteins. J. Bacteriol. 182: 637-646 [Abstract] [Full Text]  
• Welz, D., Braun, V. (1998). Ferric Citrate Transport of Escherichia coli: Functional Regions of the FecR Transmembrane Regulatory Protein. J. Bacteriol. 180: 2387-2394 [Abstract] [Full Text]  
• Wei, J., Theil, E. C. (2000). Identification and Characterization of the Iron Regulatory Element in the Ferritin Gene of a Plant (Soybean). J. Biol. Chem. 275: 17488-17493 [Abstract] [Full Text]