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J. Bacteriol., 03 1995, 1630-1633, Vol 177, No. 6
Copyright © 1995, American Society for Microbiology

Identification of a Bacillus subtilis spo0H allele that is necessary for suppression of the sporulation-defective phenotype of a spo0A mutation

MG Bramucci, BD Green, N Ambulos and P Youngman
Department of Microbiology and Immunology, Hahnemann University, Philadelphia, Pennsylvania 19102.

A mutation in Bacillus subtilis spo0A codon 97 suppressed the sporulation defect caused by the spo0A9V mutation. The suppressor activity of the codon 97 mutation was evident only in the presence of a novel spo0H allele. Our results suggest that the spo0A gene product interacts with the sigma factor subunit of RNA polymerase.


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