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J. Bacteriol., Jul 1996, 3877-3884, Vol 178, No. 13
Copyright © 1996, American Society for Microbiology

FtsZ ring formation in fts mutants

SG Addinall, E Bi and J Lutkenhaus
Department of Microbiology, Molecular Genetics and Immunology, Kansas 66160, USA.

The formation of FtsZ rings (Z rings) in various fts mutants was examined by immunoelectron microscopy and immunofluorescence. In two temperature-sensitive ftsZ mutants which form filaments with smooth morphology, the Z ring was unable to form. In ftsA, ftsI, and ftsQ mutants, which form filaments with an indented morphology, Z rings formed but their contraction was blocked. These results indicate that fully functional ftsA, ftsQ, and ftsI genes are not required for Z-ring formation and are unlikely to have a role in localization of the Z ring. The results also suggest that one function of the Z ring is to localize the activity of other fts gene products.


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