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J. Bacteriol., 07 1996, 4294-4296, Vol 178, No. 14
Copyright © 1996, American Society for Microbiology

Overexpression of vsr in Escherichia coli is mutagenic

KM Doiron, S Viau, M Koutroumanis and CG Cupples
Biology Department, Concordia University, Montreal, Quebec, Canada.

Overexpression of vsr in Escherichia coli stimulates transition and frameshift mutations. The pattern of mutations suggests that mutagenesis is due to saturation or inactivation of dam-directed mismatch repair.


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