Identification of LytSR-regulated genes from Staphylococcus aureus

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J. Bacteriol., 10 1996, 5810-5812, Vol 178, No. 19
Copyright © 1996, American Society for Microbiology

Identification of LytSR-regulated genes from Staphylococcus aureus

EW Brunskill and KW Bayles
Program in Molecular and Cell Biology, University of Maryland, Baltimore County 21228, USA.

In this report, the characterization of a Staphylococcus aureus operon containing two LytSR-regulated genes, lrgA and lrgB, is described. Sequence and mutagenesis studies of these genes suggest that lrgA encodes a murein hydrolase exporter similar to bacteriophage holin proteins while lrgB may encode a protein having murein hydrolase activity.

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