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J. Bacteriol., 10 1996, 6064-6066, Vol 178, No. 20
Copyright © 1996, American Society for Microbiology

A two-component response regulator, gltR, is required for glucose transport activity in Pseudomonas aeruginosa PAO1

AE Sage, WD Proctor and PV Phibbs Jr
Department of Microbiology and Immunology, East Carolina University School of Medicine, Greenville, North Carolina 27858-4354, USA.

A 729-bp open reading frame (gltR) was identified in Pseudomonas aeruginosa PAO1 that encodes a product homologous to the two-component response regulator family of proteins. Disruption of gltR caused loss of glucose transport activity. Restoration of gltR resulted in wild- type levels of glucose transport. These findings indicate that gltR is required for expression of the glucose transport system in P. aeruginosa.


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