J. Bacteriol., Apr 1996, 2450-2454, Vol 178, No. 8
Copyright © 1996, American Society for Microbiology

Autogenous regulation of the Bacillus subtilis glnRA operon

SW Brown and AL Sonenshein
Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.

Purified Bacillus subtilis GlnR was shown to bind with high affinity to a specific region that overlaps with the glnRA promoter site. The GlnR binding site includes four copies of a repeated sequence that may be the recognition site for the protein. GlnR inhibited transcription from the glnRA promoter in vitro.

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