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J. Bacteriol., May 1996, 2715-2717, Vol 178, No. 9
Copyright © 1996, American Society for Microbiology

Integration host factor amplifies the induction of the aceBAK operon of Escherichia coli by relieving IclR repression

E Resnik, B Pan, N Ramani, M Freundlich and DC LaPorte
Department of Biochemistry, University of Minnesota, Minneapolis 55455, USA.

A binding site for integration host factor (IHF) was identified upstream of the aceBAK promoter. Under inducing conditions, IHF activates aceB::lacZ expression by opposing IclR repression. In contrast, IHF has little effect on aceB::lacZ expression under repressing conditions. The ability of IHF to relieve repression under inducing but not repressing conditions allows this protein to amplify the induction of aceBAK.


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