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Vol. 180, Issue 13, 3474-3476, July 1, 1998

NOTE
Identification of the Repressor-Encoding Gene of the Lactobacillus Bacteriophage A2

Victor Ladero, Pilar García, Victoria Bascarán, Mónica Herrero, Miguel A. Alvarez, and Juan E. Suárez

Area de Microbiología and Instituto Universitario de Biotecnología, Universidad de Oviedo, 33006 Oviedo, Spain

The repressor gene of the Lactobacillus phage A2 has the following properties: it (i) encodes a 224-residue polypeptide with DNA binding and RecA cleavage motifs, (ii) is expressed in lysogenic cultures, and (iii) confers superinfection immunity on the host. Adjacent, but divergently transcribed, lies another open reading frame whose product resembles the lambda  Cro protein. In the 161-bp intergenic segment, putative promoters and operators have been detected.


Copyright © 1998 by American Society for Microbiology


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