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Journal of Bacteriology, September 1998, p. 4960-4962, Vol. 180, No. 18
0021-9193/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Influence of Lif, the Lysostaphin Immunity Factor, on Acceptors of Surface Proteins and Cell Wall Sorting Efficiency in Staphylococcus carnosus

Andreas Strauss, Günther Thumm, and Friedrich Götz*

Lehrstuhl für Mikrobielle Genetik, Universität Tübingen, 72076 Tübingen, Germany

Received 6 April 1998/Accepted 15 July 1998

Proteins harboring a C-terminal cell wall sorting signal are covalently linked to pentaglycine acceptors within the staphylococcal peptidoglycan. This pentaglycine was modified when the lysostaphin immunity factor (Lif) of Staphylococcus simulans was expressed in Staphylococcus carnosus, likely by the exchange of two glycine residues for serine residues. A reporter protein was efficiently linked to the modified acceptor, indicating that the sorting reaction is not strictly dependent on the wild-type structures of the acceptors.

* Corresponding author. Mailing address: Lehrstuhl für Mikrobielle Genetik, Universität Tübingen, Waldhäuserstrasse 70/8, 72076 Tübingen, Germany. Phone: (49) 7071-2978855. Fax: (49) 7071-295937. E-mail: friedrich.goetz{at}uni-tuebingen.de.

Journal of Bacteriology, September 1998, p. 4960-4962, Vol. 180, No. 18
0021-9193/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

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