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Journal of Bacteriology, December 1998, p. 6384-6388, Vol. 180, No. 23
0021-9193/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

N-Acyl-L-Homoserine Lactone Autoinducers Control Production of an Extracellular Lipopeptide Biosurfactant Required for Swarming Motility of Serratia liquefaciens MG1

P. W. Lindum,1 U. Anthoni,2 C. Christophersen,2 L. Eberl,3 S. Molin,1 and M. Givskov1,*

Department of Microbiology, Technical University of Denmark, 2800 Lyngby,1 and Marine Chemistry Section, H. C. Ørsted Institute, University of Copenhagen, 2100 Copenhagen,2 Denmark, and Lehrstuhl für Mikrobiologie, Technische Universität München, D-80290 München, Germany3

Received 15 May 1998/Accepted 23 September 1998

A nonswarming Serratia liquefaciens mutant deficient in serrawettin W2 production was constructed by transposon mutagenesis. Sequence homology indicated that insertion had occurred in gene swrA, which encodes a putative peptide synthetase. Expression of swrA is controlled by quorum sensing.

* Corresponding author. Mailing address: Department of Microbiology, Bldg. 301, Technical University of Denmark, 2800 Lyngby, Denmark. Phone: 45 45252769. Fax: 45 45932809. E-mail: mg{at}im.dtu.dk.

Journal of Bacteriology, December 1998, p. 6384-6388, Vol. 180, No. 23
0021-9193/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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