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J Bacteriol, February 1998, p. 753-758, Vol. 180, No. 3
0021-9193/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Analysis of Bacillus subtilis tagAB and tagDEF Expression during Phosphate Starvation Identifies a Repressor Role for PhoP~P

Wei Liu, Stephen Eder, and F. Marion Hulett*

Laboratory for Molecular Biology, University of Illinois at Chicago, Chicago, Illinois 60607

Received 18 August 1997/Accepted 4 December 1997

The tagAB and tagDEF operons, which are adjacent and divergently transcribed, encode genes responsible for cell wall teichoic acid synthesis in Bacillus subtilis. The Bacillus data presented here suggest that PhoP and PhoR are required for direct repression of transcription of the two operons under phosphate starvation conditions but have no regulatory role under phosphate-replete conditions. These data identify for the first time that PhoP~P has a negative role in Pho regulon gene regulation.

* Corresponding author. Mailing address: Laboratory for Molecular Biology, University of Illinois at Chicago, Chicago, IL 60607. Phone: (312) 996-5460. Fax: (312) 413-2691. E-mail: U09495{at}uicvm.uic.edu.




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