JB
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Reinders, A.
Right arrow Articles by De Virgilio, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Reinders, A.
Right arrow Articles by De Virgilio, C.

 Previous Article  |  Next Article 

Journal of Bacteriology, August 1999, p. 4665-4668, Vol. 181, No. 15
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

The Thermophilic Yeast Hansenula polymorpha Does Not Require Trehalose Synthesis for Growth at High Temperatures but Does for Normal Acquisition of Thermotolerance

Anke Reinders, Ivano Romano, Andres Wiemken, and Claudio De Virgilio*

Botanisches Institut der Universität, CH-4056 Basel, Switzerland

Received 14 April 1999/Accepted 24 May 1999

The TPS1 gene from Hansenula polymorpha, which encodes trehalose-6-phosphate (Tre6P) synthase, has been isolated and characterized. The deletion of TPS1 rendered H. polymorpha cells incapable of trehalose synthesis under conditions where wild-type cells normally accumulate high levels of trehalose. Interestingly, the loss of Tre6P synthase did not cause any obvious growth defects on a glucose-containing medium, even at high temperatures, but seriously compromised the cells' ability to acquire thermotolerance.


* Corresponding author. Mailing address: Botanisches Institut der Universität, Hebelstrasse 1, CH-4056 Basel, Switzerland. Phone: 41-61-267 2311. Fax: 41-61-267 2330. E-mail: devirgilioc{at}ubaclu.unibas.ch.


Journal of Bacteriology, August 1999, p. 4665-4668, Vol. 181, No. 15
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.



This article has been cited by other articles:




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Appl. Environ. Microbiol. Infect. Immun. Eukaryot. Cell
Mol. Cell. Biol. J. Virol. Microbiol. Mol. Biol. Rev.
ALL ASM JOURNALS

Copyright © 1999 by the American Society for Microbiology. All rights reserved.