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Journal of Bacteriology, August 1999, p. 4708-4710, Vol. 181, No. 15
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Gene Organization of the dnaA Region of Wolbachia

Ling V. Sun,1 Alekos Babaratsas,2 Charalambos Savakis,2,3 Scott L. O'Neill,1 and Kostas Bourtzis1,2,*

Department of Epidemiology & Public Health, Yale University School of Medicine, New Haven, Connecticut 06520,1 and Insect Molecular Genetics Group, Institute of Molecular Biology and Biotechnology, FORTH,2 and Division of Medical Sciences, Medical School, University of Crete,3 Heraklion, Crete, Greece

Received 4 November 1998/Accepted 13 May 1999

The dnaA region of Wolbachia, an intracellular bacterial parasite of insects, is unique. A glnA cognate was found upstream of the dnaA gene, while neither of the two open reading frames detected downstream of dnaA has any homologue in the database. This unusual gene arrangement may reflect requirements associated with the unique ecological niche this agent occupies.


* Corresponding author. Mailing address: Insect Molecular Genetics Group, Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Crete, Greece. Phone: 30 81 39 45 41. Fax: 30 81 39 11 01. E-mail: bourtzis{at}imbb.forth.gr.


Journal of Bacteriology, August 1999, p. 4708-4710, Vol. 181, No. 15
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.